In a two-volume, special edition, AICRJ volume 44, issues 2 and 3, we examine COVID-19’s unique implications for Indigenous Peoples, nations, and communities. Within the United States, African Americans, Hispanics, and American Indians have experienced substantially higher levels of COVID-19 infection and death. The impact of COVID-19 on Indigenous Peoples residing in other countries differs according to the overall national strategy for dealing with the pandemic. The structural racism of colonialism is the driver of myriad negative outcomes for Indigenous Peoples, and the effects of COVID-19 are no exception. The articles in this first special issue take a granular and intersectional look at the impact of the pandemic, the resilience of Indigenous communities, and the relevance of self-determination in public responses. These articles document specific programs and methods to combat and cope with COVID-19 effects in Indigenous communities and nations.

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