To compare the success of perceived pulpal anesthesia between groups using nitrous oxide/oxygen (N2O/O2) and oxygen (O2) in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. Thirty-three children (mean age 10.4 ± 1.9 years) with 33 symptomatic irreversible pulpitis permanent teeth were included in this preliminary study. All children were premedicated with ibuprofen and randomly assigned to receive either N2O/O2 (17 participants) or O2 (16 participants). Four percent articaine with epinephrine 1:100,000 was administered, and vital pulp therapy was performed. Children used the Wong-Baker FACES Pain Rating Scale (WBFPS) to report their pain at baseline as well as during carious dentin removal, pulpal exposure, and pulpal tissue removal steps. The success was determined when the reported WBFPS score was ≤4. The chi-square test was used to compare the success between both groups. The success of pulpal anesthesia was 71% (12/17) and 19% (3/16) in the N2O/O2 and O2 groups, respectively. The success in the N2O/O2 group was 52% higher than that in the O2 group (confidence interval = 22.9% to 80.7%; significant difference p = .003). From the result of this preliminary study, N2O/O2 significantly increased the success of perceived pulpal anesthesia in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. However, further study with a larger sample is required to confirm this result.
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Fall 2018
Research Article|
September 01 2018
Effect of Nitrous Oxide on Pulpal Anesthesia: A Preliminary Study
Papimon Chompu-inwai, DDS, MS;
Papimon Chompu-inwai, DDS, MS
*Division of Pediatric Dentistry, Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand
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Sophon Simprasert, DDS, MS;
Sophon Simprasert, DDS, MS
†Former postgraduate student in pediatric dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand
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Patchanee Chuveera, DDS, MIPH;
Patchanee Chuveera, DDS, MIPH
‡Department of Family and Community Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand
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Areerat Nirunsittirat, DDS, MS, PhD;
Areerat Nirunsittirat, DDS, MS, PhD
‡Department of Family and Community Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand
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Thanapat Sastraruji, PhD;
Thanapat Sastraruji, PhD
§Dental Research Center, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand
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Tanida Srisuwan, DDS, MS, PhD
Tanida Srisuwan, DDS, MS, PhD
||Division of Endodontics, Department of Restorative Dentistry and Periodontology, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand
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Anesth Prog (2018) 65 (3): 156–161.
Citation
Papimon Chompu-inwai, Sophon Simprasert, Patchanee Chuveera, Areerat Nirunsittirat, Thanapat Sastraruji, Tanida Srisuwan; Effect of Nitrous Oxide on Pulpal Anesthesia: A Preliminary Study. Anesth Prog 1 September 2018; 65 (3): 156–161. doi: https://doi.org/10.2344/anpr-65-02-08
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