ABSTRACT

Objectives

To evaluate the effect of orthodontic appliances on physicochemical, biochemical, and oxidative stress changes in salivary parameters during treatment.

Materials and Methods

A cohort study was conducted with 112 healthy patients. Salivary samples were taken at baseline, 1 month, and 9 months after placement of the orthodontic appliances used in treatment.

Results

A statistically significant difference was observed in certain examined salivary parameters, including enzymes, electrolytes, and oxidative stress markers.

Conclusions

The use of aligners had a lower prevalence of disturbing salivary parameters. Orthodontist must consider these changes to prevent the occurrence of white spot lesions.

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Author notes

a

Professor, Laboratory of Oral Health and Orofacial Rehabilitation, Orthodontic Department, University of Monastir, Tunisia.

b

Assistant Professor, Laboratory for Research on Biologically Compatible Compounds, Faculty of Dental Medicine, University of Monastir; Medicine Faculty of Sousse, University of Sousse, Tunisia.

c

Laboratory of Transmissible Diseases and Biologically Active Substances, University of Monastir, Tunisia; University of Tunis El Manar, Faculty of Medicine of Tunis, Department of Basic Sciences, Tunisia.

d

Private practice, Monastir, Tunisia.

e

Professor, Laboratory of Biochemistry-Toxicology, University of Monastir, Tunisia.

f

Professor, Laboratory of Infectious Diseases and Biological Agents, Monastir, Tunisia.