To discern the effects of computer-aided design (CAD)/computer-aided manufactured (CAM) customized appliances and piezocision on orthodontic treatment (OT).
The study combined findings from two previously published randomized controlled trials: (1) standard OT vs piezocision-assisted standard OT, and (2) CAD/CAM OT vs piezocision-assisted CAD/CAM OT. Piezocision is a minimally invasive corticotomy surgical procedure used to accelerate orthodontic treatment and CAD/CAM refers to CAD/CAM customized brackets and archwires. The outcomes were the overall treatment time, and the durations of the alignment phase and fine-tuning phase. Clinical and radiological features also were evaluated.
The combined study included 48 patients with similar baseline characteristics. Compared to the standard treatment, CAD/CAM technology alone significantly decreased the overall median OT time from 543 to 394 days (P < .001) and from 543 to 254 days (P < .0001) when combined with piezocision. Although piezocision significantly reduced the duration of the alignment phase in the mandible and maxilla, CAD/CAM technology considerably shortened the fine-tuning phase. All periodontal and radiographic parameters remained stable from the start to the end of treatment in all groups.
CAD/CAM technology combined with piezocision accelerates the entire OT process, during the alignment phase for piezocision and during the fine-tuning phase for CAD/CAM, with a global reduction of the overall treatment time of more than 50%.
Associate Professor, Université Côte d'Azur, Laboratoire Microbiologie orale Immunité Santé MICORALIS (Unité Propre de Recherche 7354), Faculté de Chirurgie Dentaire, Centre Hospitalier Universitaire de Nice, Nice, France; and Researcher, Dental Biomaterials Research Unit (d-BRU), University of Liège, Liège, Belgium.
Postdoctoral Researcher, Dental Biomaterials Research Unit (d-BRU) and Department of Periodontology, Oral Surgery and Implant Surgery, University Hospital of Liège, Liège, Belgium.
Biostatistician, Biostatistics and Medico-Economic Information Department, University Hospital of Liège, Liège, Belgium.
Professor Emeritus, Department of Public Health, University of Liège, Liège, Belgium.
Professor and Head, Department of Periodontology, Oral Surgery and Implant Surgery, University Hospital of Liège; and Co-Director, Dental Biomaterials Research Unit (d-BRU), University of Liège, Liège, Belgium.