This study is based on the statement that arid environment and type of mineral content of rocks work together as a catalyst for absorption of higher rates of solar irradiation that will inevitably increase vulnerability to cancer morbidity in the Northern State of Sudan. Sources are published data on climate and geology of Sudan, records of the Ministry of Health and National Population-based Cancer Registry (NCR), and the Internet. Analytical and derivational approaches were applied. The results reveal that the Northern State is a typical arid environment where four solar irradiation regions were distinguished, receiving the highest levels of solar irradiation over the Sudan. The population of the Northern State are susceptible to solar irradiation rates of 6.4 and 6.2 GHI respectively. The majority of rocks belong to silicate minerals groups with dominance of granite rocks with a chemical composition by weight of 72.04% of silica (SiO2). The general average of the solar absorb factor for the three major rock groups was 63.33%. They are inherently acquiring higher ability of absorption of solar irradiation. A general conclusion is that the ecological approach for understanding the etiology of cancer in Sudan is critical.

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