Current treatments for bedwetting (enuresis) include alarm therapy, desmopressin acetate therapy, anticholinergic therapy, and imipramine therapy. These treatments do not always eliminate the problem, and the patient often relapses when the treatment is discontinued. Surgery may be indicated for patients with anatomical abnormalities, but the vast majority of patients have normal urinary anatomy. We have found that it is usually possible to eliminate the problem using quantitative electroencephalography (QEEG)-guided neurofeedback. We report here the successful elimination of enuresis in 11 consecutive patients using this approach. Thus far, there have been no failures with this approach.

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