LORETA Neurofeedback Combined with Biofeedback as a Treatment for Agenesis of the Corpus Callosum: A Single Case Study

Agenesis of the corpus callosum (AgCC) is a congenital disorder that leads to a broad array of symptoms including cognitive, motor, and social difficulties. Parents of children with AgCC are faced with few treatment options for this often debilitating disorder. There is also a lack of research concerning how to help children and adults with AgCC achieve improved levels of functioning. This paper discusses the utility of low resolution brain electromagnetic tomography (LORETA) Z-score based neurofeedback combined with heart rate variability (HRV) training biofeedback in treating a young man with partial and congenital AgCC. The comprehensive assessment process included analysis of 19-channel quantitative-EEG (QEEG) and HRV data in combination with parent rating questionnaires, and continuous performance test measures: Integrated Visual and Auditory Continuous Performance Test (Arble, Kuentzel & Burnett, 2014) and the Test of Variables of Attention (Forbes 1998). This article illustrates amelioration of cognitive, motor, social, and sleep-based symptoms in this case, suggesting neurofeedback and biofeedback have a positive role to play in helping people with AgCC.