In the past decades, herpetologists have studied intensively the amphibians of Bolivia, increasing dramatically the number of species known for the country. There are currently 266 species recorded, but this number will increase with the addition of many new country records and the description of species new to science, especially within Andean Craugastoridae. Deforestation, habitat destruction (mostly due to agriculture), water pollution, and chytridiomycosis are the main causes of amphibian declines in Bolivia. Andean frogs are much more affected than lowland species. Infection by the chytrid fungus Batrachochytrium dendrobatidis is widespread. Forest species of the Andean genus Telmatobius have disappeared from known sites and some other Andean taxa have declined severely. Here, we revise the International Union for Conservation of Nature conservation status categories for some species of anurans. Public awareness is increasing thanks to different local initiatives addressing projects to protect Bolivian amphibians.