Background This meta-analysis highlights the diagnostic efficacy of computed tomography (CT), computed tomography angiography (CTA), magnetic resonance image (MRI), as well as magnetic resonance spectroscopy (MRS). This paper assesses the detection of the primary outcome comprising choline/creatine (Cho/Cr) ratio, relative cerebral blood volume (rCBV), as well as choline/N-acetyl aspartate (Cho/NAA). Cochrane, Medline, ScienceDirect, Google Scholar, and EMBASE databases were searched for extracting the relevant studies. Methods A sample of 12 studies on radiological assessment of brain tumors was selected. Results The evidence provides that the heterogeneity exists concerning the CBV of 311.623, I2 = 96.12%, with a significance value of (p) < 0.001. The pooled difference showed rCBV mean (as 2.18, 95%CI = 0.85 to 3.50) substantially enhances lesion. Conclusion The study concluded that radiological interventions, particularly the combination of MRS and MRI, help in the brain patient’s precise diagnosis and treatment.

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