A 16-month-old Labrador retriever was presented for evaluation and treatment of nasal aspergillosis. Intranasal clotrimazole was administered to treat the condition. The dog was anesthetized on two occasions to facilitate drug administration. Following the first treatment, the dog developed mild pharyngitis but no other complications. Inflammation and edema of the pharynx resulted in upper-airway obstruction following the second treatment. Pentobarbital sedation was used to maintain the endotracheal tube until the obstruction was relieved. Recovery following sedation was extremely prolonged. This case illustrates two adverse drug reactions: severe pharyngitis and edema (probably a result of the vehicles present in the clotrimazole formulation) and prolonged recovery (possibly the result of microsomal enzyme inhibition by the clotrimazole).
Skip Nav Destination
Article navigation
1 May 1997
Articles|
May 01 1997
Upper-airway obstruction and prolonged recovery from anesthesia following intranasal clotrimazole administration
J Am Anim Hosp Assoc (1997) 33 (3): 264–267.
Citation
N Caulkett, L Lew, C Fries; Upper-airway obstruction and prolonged recovery from anesthesia following intranasal clotrimazole administration. J Am Anim Hosp Assoc 1 May 1997; 33 (3): 264–267. doi: https://doi.org/10.5326/15473317-33-3-264
Download citation file:
Sign in
Don't already have an account? Register
Client Account
You could not be signed in. Please check your email address / username and password and try again.
Could not validate captcha. Please try again.
Sign in via your Institution
Sign in via your InstitutionCiting articles via
Long-Term Survival of Primary Intracranial Histiocytic Sarcoma Through Surgical Resection and Low-Dose CCNU
Kyosuke Hidari, DVM, Yuya Nakamoto, DVM, PhD, James K. Chambers, DVM, PhD, Kazuyuki Uchida, DVM, PhD, Isao Mori, DVM, Miwa Nakamoto, DVM
Microfilaria in the Urine of a Dog with Concurrent Urinary Bladder Sarcoma
Nicole Schlette, DVM, Erin Burton, DVM, MS, DACVP, Amber Harris, DVM, DACVIM (Internal Medicine), Kendall Langsten, DVM, DACVP, Erik Olson, DVM, PhD, DACVP, Daniel Heinrich, DVM, DACVP
Chronic Myelomonocytic Leukemia with Central Nervous System Involvement in a Dog
Ilaria Tartari, DVM, Fabio Tocco, DVM, Giorgio Cancedda, DVM, Veronica Angioni, DVM, Marco Podda, DVM, Antonella Gallucci, DVM, PhD, DECVN, EBVS
Treatment Outcomes of Canine Orbital Meningiomas in Seven Cases
Akihiro Uno, DVM, Ryota Iwasaki, DVM, PhD, Takashi Mori, DVM, PhD
Transient Hypoadrenocorticism in a 7-Week-Old Kitten
Alba Planas Vintro, BVM, Linda G. Martin, DVM, MS, DACVECC, Cassidy L. Cordon, DVM, Sabrina N. Hoehne, Dr. med. vet., DACVECC, DECVECC, Elizabeth B. Davidow, DVM, DACVECC