A six-year-old, neutered male golden retriever was presented for evaluation of stranguria. Upon physical examination, the dog was thin and actively was straining to urinate. A large, firm bladder was palpated. Urethral pressure profilometry was indicative of a focal, nondistensible lesion in the midurethra which was confirmed with a positive contrast urethrogram. Ultrasonographically, a well-marginated tubular mass was visualized midurethra, and a region of small bowel was noted to have an annular mural thickening with corrugations of the mucosal surface. The abnormal areas were aspirated percutaneously, and lymphoma was diagnosed upon cytological examination of the aspirated material. At necropsy, a diagnosis of diffuse T-cell lymphoma was confirmed.

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