A 9-year-old, spayed female domestic shorthair cat presented for polyphagia, polydipsia, and polyuria following chronic methylprednisolone acetate therapy for pruritus. Initial diagnostics were consistent with uncomplicated diabetes mellitus. Serum calcium was within reference range. Within 12 hours the cat developed depression, anorexia, vomiting, and severe dehydration. Laboratory analysis indicated marked hypercalcemia as measured by both ionized and total calcium concentration. No underlying neoplastic or inflammatory process was identified. An adrenocorti-cotropic hormone stimulation test was indicative of adrenocortical insufficiency. The hypercalcemia resolved with glucocorticoid supplementation and correction of the dehydration. The diabetes mellitus and adrenal insufficiency both resolved within 9 weeks.
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January/February 2002
Internal Medicine|
January 01 2002
Hypercalcemia Due to Iatrogenic Secondary Hypoadrenocorticism and Diabetes Mellitus in a Cat
Stephanie A. Smith, DVM, MS, Diplomate ACVIM;
Stephanie A. Smith, DVM, MS, Diplomate ACVIM
Departments of Clinical Sciences (Smith, Bagladi-Swanson) and Anatomy and Physiology (Freeman), College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66506
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Lisa C. Freeman, DVM, PhD;
Lisa C. Freeman, DVM, PhD
Departments of Clinical Sciences (Smith, Bagladi-Swanson) and Anatomy and Physiology (Freeman), College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66506
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Mary Bagladi-Swanson, DVM, Diplomate ACVD
Mary Bagladi-Swanson, DVM, Diplomate ACVD
Departments of Clinical Sciences (Smith, Bagladi-Swanson) and Anatomy and Physiology (Freeman), College of Veterinary Medicine, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66506
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J Am Anim Hosp Assoc (2002) 38 (1): 41–44.
Citation
Stephanie A. Smith, Lisa C. Freeman, Mary Bagladi-Swanson; Hypercalcemia Due to Iatrogenic Secondary Hypoadrenocorticism and Diabetes Mellitus in a Cat. J Am Anim Hosp Assoc 1 January 2002; 38 (1): 41–44. doi: https://doi.org/10.5326/0380041
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