This study determined the extent and duration of cutaneous acidification caused by a single application of four acidifying sprays, vinegar, and water. Multivariate repeated measures analysis of variance revealed a significant difference between the six sprays (F=15.3; P≤0.001). Linear contrast tests showed that the effects of the acidifying sprays were significantly different from vinegar and water (F=6.0; P≤0.001), and vinegar was significantly different from water (F=13.8; P≤0.001). The acidifying sprays decreased cutaneous pH to <6.0 for a mean range of 50 to 65 hours, while vinegar did so for a mean of 12 hours.

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