Dear Editor,

Dr. Chanoit’s review of the use of creatine kinase (CK) is very valuable, and some of his suggestions may be incorporated into future studies. However, the primary purpose of this study was to describe a laparoscopic technique to perform ovariohysterectomy in the dog. Additional studies evaluating pain levels and postoperative complications may also be performed in the future. Our brief evaluation of CK by two individual readings was a pilot study design to determine if this simple protocol may be used in future studies as a means of comparison with open techniques. Because of the constraints of our study performed on adoptable shelter animals, multiple samples were not feasible.

We would also like to address some of Dr. Chanoit’s questions regarding variables affecting CK. The intramuscular (IM) injections of acepromazine used on each dog were all of the same concentration, pH, osmolarity, and type of vehicle, and the...

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