Hematological parameters, plasma C-reactive protein (CRP), and tumor necrosis factor αwere analyzed in 64 dogs with a presumptive diagnosis of pyometra. Final diagnosis (i.e., pyometra or cystic endometrial hyperplasia [CEH]) was determined by histopathology. As a single test, the percentage of band neutrophils had the highest sensitivity in the prediction of pyometra (sensitivity, 94%). The combination of percentage of bands and CRP had the highest sensitivity (97.7%; specificity, 75%) in predicting the presence of pyometra. The most common clinical signs noted in the study were vaginal discharge, polyuria, polydipsia, lethargy, and gastrointestinal signs. A combination of three or more of these clinical signs was significantly associated with pyometra.
Skip Nav Destination
Article navigation
September/October 2004
Reproduction|
September 01 2004
C-reactive Protein in the Differentiation of Pyometra From Cystic Endometrial Hyperplasia/Mucometra in Dogs
Boel A. Fransson, DVM, PhD, Diplomate ACVS;
Boel A. Fransson, DVM, PhD, Diplomate ACVS
Departments of Veterinary Clinical Sciences (Fransson, Ragle), Animal Science (Park), and Statistics (Evans), Washington State University, Pullman, Washington 99164-7060; the
Department of Pathology (Karlstam), National Veterinary Institute, 750 07 Uppsala, Sweden; and the
Department of Small Animal Clinical Sciences (Bergstrom, Lagerstedt), Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden
From the
Search for other works by this author on:
Erika Karlstam, DVM;
Erika Karlstam, DVM
Departments of Veterinary Clinical Sciences (Fransson, Ragle), Animal Science (Park), and Statistics (Evans), Washington State University, Pullman, Washington 99164-7060; the
Department of Pathology (Karlstam), National Veterinary Institute, 750 07 Uppsala, Sweden; and the
Department of Small Animal Clinical Sciences (Bergstrom, Lagerstedt), Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden
From the
Search for other works by this author on:
Annika Bergstrom, DVM;
Annika Bergstrom, DVM
Departments of Veterinary Clinical Sciences (Fransson, Ragle), Animal Science (Park), and Statistics (Evans), Washington State University, Pullman, Washington 99164-7060; the
Department of Pathology (Karlstam), National Veterinary Institute, 750 07 Uppsala, Sweden; and the
Department of Small Animal Clinical Sciences (Bergstrom, Lagerstedt), Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden
From the
Search for other works by this author on:
Anne-Sofie Lagerstedt, DVM, PhD;
Anne-Sofie Lagerstedt, DVM, PhD
Departments of Veterinary Clinical Sciences (Fransson, Ragle), Animal Science (Park), and Statistics (Evans), Washington State University, Pullman, Washington 99164-7060; the
Department of Pathology (Karlstam), National Veterinary Institute, 750 07 Uppsala, Sweden; and the
Department of Small Animal Clinical Sciences (Bergstrom, Lagerstedt), Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden
From the
Search for other works by this author on:
Jean S. Park, PhD;
Jean S. Park, PhD
Departments of Veterinary Clinical Sciences (Fransson, Ragle), Animal Science (Park), and Statistics (Evans), Washington State University, Pullman, Washington 99164-7060; the
Department of Pathology (Karlstam), National Veterinary Institute, 750 07 Uppsala, Sweden; and the
Department of Small Animal Clinical Sciences (Bergstrom, Lagerstedt), Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden
From the
Search for other works by this author on:
Marc A. Evans;
Marc A. Evans
Departments of Veterinary Clinical Sciences (Fransson, Ragle), Animal Science (Park), and Statistics (Evans), Washington State University, Pullman, Washington 99164-7060; the
Department of Pathology (Karlstam), National Veterinary Institute, 750 07 Uppsala, Sweden; and the
Department of Small Animal Clinical Sciences (Bergstrom, Lagerstedt), Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden
From the
Search for other works by this author on:
Claude A. Ragle, DVM, Diplomate ACVS, Diplomate ABVP
Claude A. Ragle, DVM, Diplomate ACVS, Diplomate ABVP
Departments of Veterinary Clinical Sciences (Fransson, Ragle), Animal Science (Park), and Statistics (Evans), Washington State University, Pullman, Washington 99164-7060; the
Department of Pathology (Karlstam), National Veterinary Institute, 750 07 Uppsala, Sweden; and the
Department of Small Animal Clinical Sciences (Bergstrom, Lagerstedt), Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden
From the
Search for other works by this author on:
J Am Anim Hosp Assoc (2004) 40 (5): 391–399.
Citation
Boel A. Fransson, Erika Karlstam, Annika Bergstrom, Anne-Sofie Lagerstedt, Jean S. Park, Marc A. Evans, Claude A. Ragle; C-reactive Protein in the Differentiation of Pyometra From Cystic Endometrial Hyperplasia/Mucometra in Dogs. J Am Anim Hosp Assoc 1 September 2004; 40 (5): 391–399. doi: https://doi.org/10.5326/0400391
Download citation file:
Sign in
Don't already have an account? Register
Client Account
You could not be signed in. Please check your email address / username and password and try again.
Could not validate captcha. Please try again.
Sign in via your Institution
Sign in via your InstitutionCiting articles via
Long-Term Survival of Primary Intracranial Histiocytic Sarcoma Through Surgical Resection and Low-Dose CCNU
Kyosuke Hidari, DVM, Yuya Nakamoto, DVM, PhD, James K. Chambers, DVM, PhD, Kazuyuki Uchida, DVM, PhD, Isao Mori, DVM, Miwa Nakamoto, DVM
Microfilaria in the Urine of a Dog with Concurrent Urinary Bladder Sarcoma
Nicole Schlette, DVM, Erin Burton, DVM, MS, DACVP, Amber Harris, DVM, DACVIM (Internal Medicine), Kendall Langsten, DVM, DACVP, Erik Olson, DVM, PhD, DACVP, Daniel Heinrich, DVM, DACVP
Chronic Myelomonocytic Leukemia with Central Nervous System Involvement in a Dog
Ilaria Tartari, DVM, Fabio Tocco, DVM, Giorgio Cancedda, DVM, Veronica Angioni, DVM, Marco Podda, DVM, Antonella Gallucci, DVM, PhD, DECVN, EBVS
Treatment Outcomes of Canine Orbital Meningiomas in Seven Cases
Akihiro Uno, DVM, Ryota Iwasaki, DVM, PhD, Takashi Mori, DVM, PhD
Transient Hypoadrenocorticism in a 7-Week-Old Kitten
Alba Planas Vintro, BVM, Linda G. Martin, DVM, MS, DACVECC, Cassidy L. Cordon, DVM, Sabrina N. Hoehne, Dr. med. vet., DACVECC, DECVECC, Elizabeth B. Davidow, DVM, DACVECC