Dear Dr. Roush,
Thank you for your interest and comments on our paper entitled “Proximal Radial and Distal Humeral Osteosar-coma in 12 Dogs,” published in the November-December issue of the
The reported median survival time and median metastasis-free interval are correct, and no mistake has been made by either the authors or the reviewers. Kaplan-Meier survival analysis is the standard statistical test to calculate outcome in animals and humans with oncologic disease. Kaplan-Meier survival analysis includes animals that have died from tumor-related causes or are lost to follow-up, whereas animals that are alive or have died for reasons unrelated to the tumor are censored from analysis.
In our analysis, 10 dogs with osteosarcoma of the distal humerus or proximal radius were treated with curative-intent forequarter amputation and postoperative chemotherapy. Of these 10 dogs, four died...