Propentofylline is a methylxanthine derivative with bronchodilating actions similar to those of theophylline. Nineteen cats with bronchial disease were enrolled in this study. All cats received a low dose of prednisolone; 10 of the cats additionally received propentofylline. Propentofylline-treated cats significantly improved in their auscultation scores, respiratory pattern scores, and radiological bronchial markings score over the observation period, and they coughed less and slept less at the end of the study. No significant changes were noted in the control group. This study provides evidence that a combination therapy with prednisolone and propentofylline in cats with bronchial disease might be superior over monotherapy with prednisolone.
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September/October 2010
Respiratory Diseases|
September 01 2010
Use of Propentofylline in Feline Bronchial Disease: Prospective, Randomized, Positive-Controlled Study
Ulrike Stursberg, Dr. med. vet.;
Ulrike Stursberg, Dr. med. vet.
Clinic of Small Animal Medicine, (Stursberg, Zenker, Hartmann, Schulz), Ludwig Maximilian University of Munich, Faculty of Veterinary Medicine, Munich, 80539 Germany and the
Department of Small Animal, Clinical Sciences (Hecht), College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996-4544
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Isabella Zenker;
Isabella Zenker
Veterinarian
Clinic of Small Animal Medicine, (Stursberg, Zenker, Hartmann, Schulz), Ludwig Maximilian University of Munich, Faculty of Veterinary Medicine, Munich, 80539 Germany and the
Department of Small Animal, Clinical Sciences (Hecht), College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996-4544
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Silke Hecht, Dr. med. vet., Diplomate ACVR, Diplomate ECVDI;
Silke Hecht, Dr. med. vet., Diplomate ACVR, Diplomate ECVDI
Clinic of Small Animal Medicine, (Stursberg, Zenker, Hartmann, Schulz), Ludwig Maximilian University of Munich, Faculty of Veterinary Medicine, Munich, 80539 Germany and the
Department of Small Animal, Clinical Sciences (Hecht), College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996-4544
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Katrin Hartmann, Dr. med. vet., Diplomate ECVIM-CA;
Katrin Hartmann, Dr. med. vet., Diplomate ECVIM-CA
Clinic of Small Animal Medicine, (Stursberg, Zenker, Hartmann, Schulz), Ludwig Maximilian University of Munich, Faculty of Veterinary Medicine, Munich, 80539 Germany and the
Department of Small Animal, Clinical Sciences (Hecht), College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996-4544
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Bianka S. Schulz, Dr. med. vet., Diplomate ECVIM-CA
Bianka S. Schulz, Dr. med. vet., Diplomate ECVIM-CA
Clinic of Small Animal Medicine, (Stursberg, Zenker, Hartmann, Schulz), Ludwig Maximilian University of Munich, Faculty of Veterinary Medicine, Munich, 80539 Germany and the
Department of Small Animal, Clinical Sciences (Hecht), College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996-4544
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J Am Anim Hosp Assoc (2010) 46 (5): 318–326.
Citation
Ulrike Stursberg, Isabella Zenker, Silke Hecht, Katrin Hartmann, Bianka S. Schulz; Use of Propentofylline in Feline Bronchial Disease: Prospective, Randomized, Positive-Controlled Study. J Am Anim Hosp Assoc 1 September 2010; 46 (5): 318–326. doi: https://doi.org/10.5326/0460318
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