Kidney biopsies in dogs are commonly obtained using automated spring-loaded biopsy instruments. Interpretation of biopsies from dogs with glomerular disease requires examination of at least 5–10 glomeruli, with at least two biopsies usually required for full evaluation. The purpose of this study was to compare quality and interpretability of renal biopsies obtained from healthy dogs with a large-gauge, vacuum-assisted biopsy instrument versus two biopsies obtained with a spring-loaded biopsy needle. Twenty dogs were randomized into two groups, and percutaneous, ultrasound-guided renal biopsies were evaluated using standard criteria. There were no significant differences in the number of biopsies that contained renal tissue, cortex, or medulla. Biopsies obtained with either instrument contained an adequate number of glomeruli and an equivalent number of arterioles and severity of tissue compression. Differences included easier penetration of the renal capsule and collection of sufficient tissue for interpretation with only one instrument pass when using the vacuum-assisted device (vs two passes required with the spring-loaded instrument). Before use in client-owned dogs, future studies should evaluate whether these differences are clinically relevant advantages in the diagnostic evaluation of dogs with kidney disease, and determine the prevalence and severity of complications when using this larger gauge device.
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November/December 2011
Original Studies|
November 01 2011
Pilot Evaluation of a Vacuum-Assisted Biopsy Instrument for Percutaneous Renal Biopsy in Dogs
Marina Manashirova, DVM;
Marina Manashirova, DVM
*
Department of Veterinary Clinical Sciences (M.M., B.P., H.G., H.H., L.F.) and Department of Comparative Pathobiology (S.L., H.O-A.), School of Veterinary Medicine, Purdue University, West Lafayette, IN.
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Barrak M. Pressler, PhD, DVM, DACVIM;
Barrak M. Pressler, PhD, DVM, DACVIM
†
Department of Veterinary Clinical Sciences (M.M., B.P., H.G., H.H., L.F.) and Department of Comparative Pathobiology (S.L., H.O-A.), School of Veterinary Medicine, Purdue University, West Lafayette, IN.
Correspondence: [email protected] (B.P.)
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Hylton R. Gelb, DVM, MS;
Hylton R. Gelb, DVM, MS
Department of Veterinary Clinical Sciences (M.M., B.P., H.G., H.H., L.F.) and Department of Comparative Pathobiology (S.L., H.O-A.), School of Veterinary Medicine, Purdue University, West Lafayette, IN.
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Hock Gan Heng, MVS, MS, DVM, DACVR;
Hock Gan Heng, MVS, MS, DVM, DACVR
Department of Veterinary Clinical Sciences (M.M., B.P., H.G., H.H., L.F.) and Department of Comparative Pathobiology (S.L., H.O-A.), School of Veterinary Medicine, Purdue University, West Lafayette, IN.
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Stephen D. Lenz, PhD, DVM, DACVP;
Stephen D. Lenz, PhD, DVM, DACVP
Department of Veterinary Clinical Sciences (M.M., B.P., H.G., H.H., L.F.) and Department of Comparative Pathobiology (S.L., H.O-A.), School of Veterinary Medicine, Purdue University, West Lafayette, IN.
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Hugo G. Ochoa-Acuna, MS, PhD, DVM;
Hugo G. Ochoa-Acuna, MS, PhD, DVM
§
Department of Veterinary Clinical Sciences (M.M., B.P., H.G., H.H., L.F.) and Department of Comparative Pathobiology (S.L., H.O-A.), School of Veterinary Medicine, Purdue University, West Lafayette, IN.
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Lynetta J. Freeman, MS, MBA, DVM, DACVS
Lynetta J. Freeman, MS, MBA, DVM, DACVS
Department of Veterinary Clinical Sciences (M.M., B.P., H.G., H.H., L.F.) and Department of Comparative Pathobiology (S.L., H.O-A.), School of Veterinary Medicine, Purdue University, West Lafayette, IN.
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J Am Anim Hosp Assoc (2011) 47 (6): 391–398.
Citation
Marina Manashirova, Barrak M. Pressler, Hylton R. Gelb, Hock Gan Heng, Stephen D. Lenz, Hugo G. Ochoa-Acuna, Lynetta J. Freeman; Pilot Evaluation of a Vacuum-Assisted Biopsy Instrument for Percutaneous Renal Biopsy in Dogs. J Am Anim Hosp Assoc 1 November 2011; 47 (6): 391–398. doi: https://doi.org/10.5326/JAAHA-MS-5637
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