A 9 yr old neutered male mixed-breed dog was presented for an anal sac apocrine gland adenocarcinoma with regional nodal metastases. At presentation, ionized calcium was 1.91 mmol/L (NOVA Stat reference range, 1.1–1.3 mmol/L). Surgical excision of the primary tumor and metastatic lymph nodes was performed. Following surgery, symptomatic hypocalcemia was noted. Repeated ionized calcium measurements confirmed hypocalcemia, and hypercalcemia of malignancy panels suggested parathyroid gland suppression as the cause. The calcium normalized with parenteral calcium administration, but calcium later became elevated with tumor recurrence and an increase in the parathormone-related peptide. Disrupted calcium homeostasis is a potential complication following the treatment of long-standing humoral hypercalcemia of malignancy.
Skip Nav Destination
Article navigation
November/December 2011
Online-Only Articles|
November 01 2011
Hypocalcemia Following Surgical Treatment of Metastatic Anal Sac Adenocarcinoma in a Dog
Corey Saba, DVM;
Department of Small Animal Medicine & Surgery (C.S., K.C.) and Veterinary Diagnostic Laboratory (A.E.), College of Veterinary Medicine, University of Georgia, Athens, GA.
Correspondence: [email protected] (C.S.)
Search for other works by this author on:
Angela Ellis, PhD, DVM;
Angela Ellis, PhD, DVM
Department of Small Animal Medicine & Surgery (C.S., K.C.) and Veterinary Diagnostic Laboratory (A.E.), College of Veterinary Medicine, University of Georgia, Athens, GA.
Search for other works by this author on:
Karen Cornell, PhD, DVM
Karen Cornell, PhD, DVM
Department of Small Animal Medicine & Surgery (C.S., K.C.) and Veterinary Diagnostic Laboratory (A.E.), College of Veterinary Medicine, University of Georgia, Athens, GA.
Search for other works by this author on:
J Am Anim Hosp Assoc (2011) 47 (6): e173–e177.
Citation
Corey Saba, Angela Ellis, Karen Cornell; Hypocalcemia Following Surgical Treatment of Metastatic Anal Sac Adenocarcinoma in a Dog. J Am Anim Hosp Assoc 1 November 2011; 47 (6): e173–e177. doi: https://doi.org/10.5326/JAAHA-MS-5601
Download citation file:
Sign in
Don't already have an account? Register
Client Account
You could not be signed in. Please check your email address / username and password and try again.
Could not validate captcha. Please try again.
Sign in via your Institution
Sign in via your InstitutionCiting articles via
Long-Term Survival of Primary Intracranial Histiocytic Sarcoma Through Surgical Resection and Low-Dose CCNU
Kyosuke Hidari, DVM, Yuya Nakamoto, DVM, PhD, James K. Chambers, DVM, PhD, Kazuyuki Uchida, DVM, PhD, Isao Mori, DVM, Miwa Nakamoto, DVM
Microfilaria in the Urine of a Dog with Concurrent Urinary Bladder Sarcoma
Nicole Schlette, DVM, Erin Burton, DVM, MS, DACVP, Amber Harris, DVM, DACVIM (Internal Medicine), Kendall Langsten, DVM, DACVP, Erik Olson, DVM, PhD, DACVP, Daniel Heinrich, DVM, DACVP
Chronic Myelomonocytic Leukemia with Central Nervous System Involvement in a Dog
Ilaria Tartari, DVM, Fabio Tocco, DVM, Giorgio Cancedda, DVM, Veronica Angioni, DVM, Marco Podda, DVM, Antonella Gallucci, DVM, PhD, DECVN, EBVS
Treatment Outcomes of Canine Orbital Meningiomas in Seven Cases
Akihiro Uno, DVM, Ryota Iwasaki, DVM, PhD, Takashi Mori, DVM, PhD
Transient Hypoadrenocorticism in a 7-Week-Old Kitten
Alba Planas Vintro, BVM, Linda G. Martin, DVM, MS, DACVECC, Cassidy L. Cordon, DVM, Sabrina N. Hoehne, Dr. med. vet., DACVECC, DECVECC, Elizabeth B. Davidow, DVM, DACVECC