Eighteen clinically ill dogs, naturally infected with Anaplasma phagocytophilum, were examined at a veterinary practice in Baxter, Minnesota. A clinical examination, complete blood cell count, enzyme- linked immunosorbent assay (ELISA) for A phagocytophilum, Borrelia burgdorferi, and Ehrlichia canis antibodies and Dirofilaria immitis antigen, and a polymerase chain reaction test for A phagocytophilum DNA were obtained for all dogs. Physical examination findings included fever, arthropathy, lymphadenopathy, epistaxis, acute gastritis, cervical hyperpathia, and central nervous system dysfunction. Complete blood cell count abnormalities included thrombocytopenia, morulae in neutrophils, anemia, leukopenia, eosinopenia, lymphopenia, and monocytosis. Seroreactivity to A phagocytophilum was found in 61%, B burgdorferi antibodies in 17%, and D immitis antigen in 5% of the dogs. Fever, arthropathy, neurologic dysfunction, and epistaxis are clinical syndromes that can be associated with A phagocytophilum infection. Treatment with doxycycline resulted in rapid resolution of clinical signs in all dogs.
Skip Nav Destination
Article navigation
November/December 2011
Online-Only Articles|
November 01 2011
Typical and Atypical Manifestations of Anaplasma phagocytophilum Infection in Dogs
Matthew D. Eberts, DVM;
Lakeland Veterinary Hospital, Baxter, MN (M.E.); Intracellular Pathogens Research Laboratory College of Veterinary Medicine, North Carolina State University, Raleigh, NC (P.D., E.B.); and IDEXX Laboratories, Inc, Westbrook, ME (M.B., B.S., R.C.).
Correspondence: [email protected] (M.E.)
Search for other works by this author on:
Pedro Paulo Vissotto de Paiva Diniz, PhD, DVM;
Pedro Paulo Vissotto de Paiva Diniz, PhD, DVM
*
Lakeland Veterinary Hospital, Baxter, MN (M.E.); Intracellular Pathogens Research Laboratory College of Veterinary Medicine, North Carolina State University, Raleigh, NC (P.D., E.B.); and IDEXX Laboratories, Inc, Westbrook, ME (M.B., B.S., R.C.).
Search for other works by this author on:
Melissa J. Beall, DVM;
Melissa J. Beall, DVM
Lakeland Veterinary Hospital, Baxter, MN (M.E.); Intracellular Pathogens Research Laboratory College of Veterinary Medicine, North Carolina State University, Raleigh, NC (P.D., E.B.); and IDEXX Laboratories, Inc, Westbrook, ME (M.B., B.S., R.C.).
Search for other works by this author on:
Brett A. Stillman, PhD;
Brett A. Stillman, PhD
Lakeland Veterinary Hospital, Baxter, MN (M.E.); Intracellular Pathogens Research Laboratory College of Veterinary Medicine, North Carolina State University, Raleigh, NC (P.D., E.B.); and IDEXX Laboratories, Inc, Westbrook, ME (M.B., B.S., R.C.).
Search for other works by this author on:
Ramaswamy Chandrashekar, PhD;
Ramaswamy Chandrashekar, PhD
Lakeland Veterinary Hospital, Baxter, MN (M.E.); Intracellular Pathogens Research Laboratory College of Veterinary Medicine, North Carolina State University, Raleigh, NC (P.D., E.B.); and IDEXX Laboratories, Inc, Westbrook, ME (M.B., B.S., R.C.).
Search for other works by this author on:
Edward B. Breitschwerdt, DVM
Edward B. Breitschwerdt, DVM
Lakeland Veterinary Hospital, Baxter, MN (M.E.); Intracellular Pathogens Research Laboratory College of Veterinary Medicine, North Carolina State University, Raleigh, NC (P.D., E.B.); and IDEXX Laboratories, Inc, Westbrook, ME (M.B., B.S., R.C.).
Search for other works by this author on:
J Am Anim Hosp Assoc (2011) 47 (6): e86–e94.
Citation
Matthew D. Eberts, Pedro Paulo Vissotto de Paiva Diniz, Melissa J. Beall, Brett A. Stillman, Ramaswamy Chandrashekar, Edward B. Breitschwerdt; Typical and Atypical Manifestations of Anaplasma phagocytophilum Infection in Dogs. J Am Anim Hosp Assoc 1 November 2011; 47 (6): e86–e94. doi: https://doi.org/10.5326/JAAHA-MS-5578
Download citation file:
Sign in
Don't already have an account? Register
Client Account
You could not be signed in. Please check your email address / username and password and try again.
Could not validate captcha. Please try again.
Sign in via your Institution
Sign in via your InstitutionCiting articles via
Long-Term Survival of Primary Intracranial Histiocytic Sarcoma Through Surgical Resection and Low-Dose CCNU
Kyosuke Hidari, DVM, Yuya Nakamoto, DVM, PhD, James K. Chambers, DVM, PhD, Kazuyuki Uchida, DVM, PhD, Isao Mori, DVM, Miwa Nakamoto, DVM
Microfilaria in the Urine of a Dog with Concurrent Urinary Bladder Sarcoma
Nicole Schlette, DVM, Erin Burton, DVM, MS, DACVP, Amber Harris, DVM, DACVIM (Internal Medicine), Kendall Langsten, DVM, DACVP, Erik Olson, DVM, PhD, DACVP, Daniel Heinrich, DVM, DACVP
Chronic Myelomonocytic Leukemia with Central Nervous System Involvement in a Dog
Ilaria Tartari, DVM, Fabio Tocco, DVM, Giorgio Cancedda, DVM, Veronica Angioni, DVM, Marco Podda, DVM, Antonella Gallucci, DVM, PhD, DECVN, EBVS
Treatment Outcomes of Canine Orbital Meningiomas in Seven Cases
Akihiro Uno, DVM, Ryota Iwasaki, DVM, PhD, Takashi Mori, DVM, PhD
Transient Hypoadrenocorticism in a 7-Week-Old Kitten
Alba Planas Vintro, BVM, Linda G. Martin, DVM, MS, DACVECC, Cassidy L. Cordon, DVM, Sabrina N. Hoehne, Dr. med. vet., DACVECC, DECVECC, Elizabeth B. Davidow, DVM, DACVECC