A 9 yr old spayed female boxer was presented for evaluation of vomiting, lethargy, anorexia, and weight loss. Initial laboratory evaluation revealed a hyperchloremic normal anion gap metabolic acidosis with alkaline urine that was consistent with a diagnosis of distal renal tubular acidosis (RTA). Targeted therapy was initiated with Na bicarbonate (HCO3) and potassium (K) gluconate. Leptospirosis was subsequently diagnosed with paired microagglutination testing (MAT), and doxycycline was added to the other treatments. Clinical signs resolved, and 6 mo after diagnosis, although the dog remained on alkali therapy (i.e., NaHCO3 and K gluconate) and a mild metabolic acidosis persisted, the dog remained otherwise healthy with a good quality of life. To the authors’ knowledge, this is the first report to describe the concomitant association of those two disorders. Leptospirosis should be considered for any case of RTA in dogs.
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May/June 2014
Case Reports|
May 01 2014
Distal Renal Tubular Acidosis Associated with Concurrent Leptospirosis in a Dog
Stephen A. Martinez, DVM, DACVIM;
Stephen A. Martinez, DVM, DACVIM
Department of Internal Medicine, MedVet Medical and Cancer Centers for Pets, Worthington, OH.
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Roger A. Hostutler, DVM, MS, DACVIM
Roger A. Hostutler, DVM, MS, DACVIM
Department of Internal Medicine, MedVet Medical and Cancer Centers for Pets, Worthington, OH.
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J Am Anim Hosp Assoc (2014) 50 (3): 203–208.
Citation
Stephen A. Martinez, Roger A. Hostutler; Distal Renal Tubular Acidosis Associated with Concurrent Leptospirosis in a Dog. J Am Anim Hosp Assoc 1 May 2014; 50 (3): 203–208. doi: https://doi.org/10.5326/JAAHA-MS-5993
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