Point-of-care testing is an attractive option in rabbit medicine, because it permits rapid analysis of a panel of electrolytes, chemistries, blood gases, hemoglobin, and hematocrit, requiring only 65 μL of blood. The purpose of this study was to evaluate the performance of a portable clinical analyzer for measurement of pH, partial pressure of CO2, Na, chloride, potassium, blood urea nitrogen, glucose, hematocrit, and hemoglobin in healthy and diseased rabbits. Blood samples obtained from 30 pet rabbits were analyzed immediately after collection by the portable clinical analyzer (PCA) and immediately thereafter (time <20 sec) by a reference analyzer. Bland-Altman plots and Passing-Bablok regression analysis were used to compare the results. Limits of agreement were wide for all the variables studied, with the exception of pH. Most variables presented significant proportional and/or constant bias. The current study provides sufficient evidence that the PCA presents reliability for pH, although its low agreement with a reference analyzer for the other variables does not support their interchangeability. Limits of agreement provided for each variable allow researchers to evaluate if the PCA is reliable enough for their scope. To the authors’ knowledge, the present is the first report evaluating a PCA in the rabbit.
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September/October 2014
Original Studies|
September 01 2014
Point-of-Care Blood Gases, Electrolytes, Chemistries, Hemoglobin, and Hematocrit Measurement in Venous Samples from Pet Rabbits
Paolo Selleri, PhD, DMV;
Paolo Selleri, PhD, DMV
Clinic for Exotic Animals, Veterinary Specialty Center, Rome, Italy (P.S., N.D.) and Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy (N.D.).
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Nicola Di Girolamo, DMV
Nicola Di Girolamo, DMV
Clinic for Exotic Animals, Veterinary Specialty Center, Rome, Italy (P.S., N.D.) and Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy (N.D.).
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J Am Anim Hosp Assoc (2014) 50 (5): 305–314.
Citation
Paolo Selleri, Nicola Di Girolamo; Point-of-Care Blood Gases, Electrolytes, Chemistries, Hemoglobin, and Hematocrit Measurement in Venous Samples from Pet Rabbits. J Am Anim Hosp Assoc 1 September 2014; 50 (5): 305–314. doi: https://doi.org/10.5326/JAAHA-MS-6114
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