A 14 mo old female Jack Russell terrier presented with a 12 hr history of vomiting and inappetence. She was subsequently diagnosed with multiple acquired portosystemic shunts during an exploratory celiotomy. Gross and histopathological hepatic abnormalities were consistent with chronic disease, including features suggestive of portal hypertension that was potentially caused by migrating and resident Angiostrongylus vasorum larvae. Fecal analysis and polymerase chain reaction of hepatic tissue confirmed the presence of Angiostrongylus vasorum. The dog recovered clinically following empirical treatment and supportive care. A lack of parasite burden was confirmed 9 wk postdiagnosis; however, serum biochemical analysis at that time was suggestive of ongoing hepatic dysfunction.
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September/October 2015
Case Reports|
September 01 2015
Angiostrongylus vasorum Causing Severe Granulomatous Hepatitis with Concurrent Multiple Acquired PSS
Simon Cook, BSc, BVSc;
Simon Cook, BSc, BVSc
From the Department of Clinical Sciences and Services (S.C., R.M.) and Department of Pathology and Pathogen Biology (S.P., D.B.), The Royal Veterinary College, University of London, Hatfield, United Kingdom (S.C.).
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Simon L. Priestnall, BSc, BVSc, PhD, PGCert(VetEd), DACVP, FRCPath, MRCVS;
Simon L. Priestnall, BSc, BVSc, PhD, PGCert(VetEd), DACVP, FRCPath, MRCVS
From the Department of Clinical Sciences and Services (S.C., R.M.) and Department of Pathology and Pathogen Biology (S.P., D.B.), The Royal Veterinary College, University of London, Hatfield, United Kingdom (S.C.).
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Damer Blake, BSc, MSc, PhD, PGCVetEd, FHEA;
Damer Blake, BSc, MSc, PhD, PGCVetEd, FHEA
From the Department of Clinical Sciences and Services (S.C., R.M.) and Department of Pathology and Pathogen Biology (S.P., D.B.), The Royal Veterinary College, University of London, Hatfield, United Kingdom (S.C.).
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Richard L. Meeson, MA, VetMB, MVetMed, DECVS, MRCVS
Richard L. Meeson, MA, VetMB, MVetMed, DECVS, MRCVS
From the Department of Clinical Sciences and Services (S.C., R.M.) and Department of Pathology and Pathogen Biology (S.P., D.B.), The Royal Veterinary College, University of London, Hatfield, United Kingdom (S.C.).
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J Am Anim Hosp Assoc (2015) 51 (5): 320–324.
Citation
Simon Cook, Simon L. Priestnall, Damer Blake, Richard L. Meeson; Angiostrongylus vasorum Causing Severe Granulomatous Hepatitis with Concurrent Multiple Acquired PSS. J Am Anim Hosp Assoc 1 September 2015; 51 (5): 320–324. doi: https://doi.org/10.5326/JAAHA-MS-6210
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