Carbapenemase-producing Enterobacterales (CPE) are an emerging public health threat in both human and veterinary medicine. As antibiotic resistance grows, there is increased importance in preventing the spread and transmission of these organisms by using appropriate infection prevention and biosecurity measures. The goal of this study was to test the efficacy of commonly used disinfectants in the veterinary setting against CPE strains. A total of 10 bacterial strains (9 CPE and 1 control strain) and 5 disinfectants were evaluated. Effective disinfection (at least a 3-log kill) was found at the manufacturer’s contact time for all strains when paired with all products except for one strain (47422-21) of Enterobacter hormaechei, which only had a 2-log for the accelerated hydrogen peroxide product and a 1-log reduction for the quaternary ammonium compound product. When used according to manufacturer recommendations, the five surface disinfectants tested were effective in vitro against the majority of CPE of animal origin that were evaluated.

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