Peripherally inserted central catheters (PICCs) are used in many different patient populations. The indications for use vary and include infusions of hyperalimentation, chemotherapeutic agents, hyperosmolar solutions, antibiotics, or long-term rehydration. However, on occasion, there are clients who do not fit the typical criteria for PICC insertion. This includes, but is not limited to, those individuals who are receiving frequent intravenous (IV) “sticks” or even short-term infusions of irritating drugs. The behavioral health client is one who may not be the typical PICC or IV patient but who may benefit from the placement of a PICC for certain treatment modalities.