Arterial diameter above 2 mm had an almost 5 times better AVF maturation outcome.
Average age of ESRD patients who underwent the AVF procedure was above 50 years.
Percentage of AVF maturation was higher in men.
Hypertension was the most common comorbid factor in ESRD patients.
Background: Arteriovenous fistula (AVF) is one of most common types of vascular access used in end-stage renal disease (ESRD) patients in renal replacement therapy. Many factors can affect the maturation of AVF. This study aimed to investigate the factors that influence AVF maturation.
Methods: Retrospective data of subjects who underwent the AVF procedure from May 1 to June 31, 2017 in South Ring Road Surgery Hospital were examined through medical records. Analysis of predictive models was done using logistic regression with backward stepwise procedure.
Results: Mature AVF occurred in 82.8% of 87 total subjects, with average AVF maturity duration of 26.6 ± 8.30 days. There was a significant difference in the average age of the subjects with regard to AVF maturation, in that the average age in the mature group and the immature group was 52.47 ± 14.5 and 45.17 ± 10.92 years, respectively (P = 0.029, Mann-Whitney). There was no significant difference between the mature group and the immature group with regard to AVF maturation in males (P = 0.361) and some comorbid factors such as diabetes mellitus (P = 0.765), hypertension (P = 0.448), smoking history (P = 0.394), and peripheral vascular disease (P = 1.000). The majority of the AVF were located in the forearm (56.3%). Arterial diameter above 2 mm resulted in a more than 4 times increase in AVF maturity (P = 0.010, odds ratio [OR] = 4.85, 95% confidence interval [95%CI]: 1.46–16.11), while venous diameter above 2 mm (P = 0.620, OR = 0.72, 95%CI: 0.20–2.59) showed no statistically significant difference in logistic regression.
Conclusions: Arterial diameter appears to be a strong predictor of AVF maturity, with outcomes being more than 4 times better with arterial diameter above 2 mm.