Alina G. Burek, MD

Purpose: The aims of this study were to (1) identify national trends and variation in CVAD (PICC and non-PICC) use outside of the intensive care unit (CVADs/total encounters); (2) describe the population of children with CVADs; (3) Determine the rate of central line-associated blood stream infections (CLABSI) and venous thromboembolism (VTE) in this population.

Background: Central venous access devices (CVADs) such as peripherally inserted central catheters (PICCs) must be used judiciously due to serious complications (CLABSI and venous thromboembolism [VTE])


  • Design: multisite retrospective study using the Pediatric Health Information System (PHIS) database

  • Population:

    • Hospitalized children (<18 years) that received a CVAD between 1/2012 and 12/2021

    • CVAD supplies and procedure codes used

    • Patients admitted to neonatal intensive care unit (NICU) and pediatric intensive care unit (PICU) excluded

  • 10-year cohort used for trends exploration

  • 5-year cohort used to compare variation between sites and further describe the...

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