Use of needleless intravenous systems are important in preventing injury and exposure to blood-borne pathogens. After insertion, patients were randomized to have either a PASV Protector, CLC2000, or CLAVE device placed on the hub of the indwelling PICC. Rates of occlusion were 11% with the CLAVE device, 4% with the CLC2000 device, and only 1% with the PASV Protector device. With use of the PASV Protector device, occlusion rates dropped significantly.

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