Objective: The objective of this study was to evaluate the remineralization effect of two different mineral containing agents on white/creamy and yellow/brown demarcated opacities in incisors in children with molar-incisor hypomineralization (MIH) by using laser fluoresence (LF). Study Design: Fifty-three children (n=401 lesions) with MIH were randomly divided into three groups: (1)calcium glycerophosphate (CaGP), (2)casein phosphopeptide amorphous calcium fluoride phosphate (CPP-ACFP) and, (3)control (1450 ppm fluoride toothpaste). Remineralization was evaluated by means of LF, at baseline, after one and threemonths. Anova Test for Repeated Measurements in intra-group comparisons in evaluating the effectiveness of remineralization agents. One-way Variance Analysis (ANOVA) and Tukey-Kramer Multiple Comparison test were used in the comparisons between groups and, Student Newman Keuls Multpile Comparison Test was used to determine the differences between the measurement averages in case of p<0.05. Results: There was a significant improvement in MIH-lesions over time in all groups (p<0.001), with no differences between groups. The highest percentage of change was observed in CPP-ACFP in lesions LF≤20 scores and the mean percentage of change LF>20 scores, the highest percentage changes in CaGP. There was no significant difference between the groups over the time for all the used outcome measures (p>0.05). Conclusion: The additional use of both mineral containing agents in MIH-affected teeth improved these hypomineralized lesions with mineral deposition. Even if both agents could be used in the hypomineralized teeth with demarcated opacities, future studies are recommended the long-term effect of these mineral containing agents with longer observation and a larger sample size.
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Research Article|
July 13 2022
Effect of Remineralization Agents on Molar-Incisor Hypomineralization-Affected Incisors: A Randomized Controlled Clinical Trial
Berkant Sezer;
*Berkant Sezer, Assistant Professor, Department of Pediatric Dentistry, School of Dentistry, Canakkale Onsekiz Mart University, Canakkale, Turkey
Corresponding Author: Berkant Sezer, Canakkale Onsekiz Mart Universitesi Dis Hekimligi Fakultesi Pedodonti, Anabilim Dali, Cumhuriyet Mah. Sahilyolu Cd. No:5, Kepez, Canakkale,, Turkey, Phone: +90 553 010 51 04., Fax : +90 286 263 36 10, E-mail: berkant.sezer@comu.edu.tr, dt.berkantsezer@gmail.com
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Betul Kargul
Betul Kargul
**Betul Kargul, Professor and Head, Department of Pediatric Dentistry, School of Dentistry, Marmara University, Istanbul, Turkey
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J Clin Pediatr Dent (2022) 46 (3): 192–198.
Citation
Berkant Sezer, Betul Kargul; Effect of Remineralization Agents on Molar-Incisor Hypomineralization-Affected Incisors: A Randomized Controlled Clinical Trial. J Clin Pediatr Dent 1 May 2022; 46 (3): 192–198. doi: https://doi.org/10.17796/1053-4625-46.3.4
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