An apparatus to determine the rate of release of chemotherapeutics from vehicles was developed. It consists of a semi-permeable chamber within a larger glass chamber. The semi-permeable chamber has direct contact with milk within the glass chamber. Preliminary evaluation for rapidity of release of chemotherapeutics by vehicles, in decreasing amount of antibiotic released, showed them to be water, sesame oil, sweet cream butter, peanut oil with aluminum monostearate, lanolin and petrolatum.

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Author notes

1Published with the Approval of the Director of the North Dakota Agricultural Experiment Station as Science Series 929.

2Department of Veterinary Medicine.

3College of Pharmacy.