A comparative assessment of the antibacterial activity of pure and mixed-strain cultures of Streptococcus thermophilus and Lactobacillus bulgaricus against Escherichia coli. Staphylococcus aureus, Pseudomonas fragi and Micrococcus flavus was made using cow and buffalo milk. A culture filtrate from S. thermophilus exhibited no antagonistic action against any of the test organisms, irrespective of the type of milk used and the period of incubation. Culture filtrates from L. bulgaricus and the mixed culture caused pronounced inhibition of all the test organisms used. Antibacterial activity of yogurt culture was greater in buffalo than cow milk.

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