Over a 3-month period, a 6-yr-old, wild-caught, northern leopard frog ( Lithobates pipiens ) presented for reoccurring cloacal prolapse, despite surgical correction. Two contrast radiographic series performed approximately 6 wk apart showed intestinal obstruction and gastrointestinal dysmotility, while exploratory coeliotomy revealed a minor intestinal intussusception. Approximately 6 months after the fourth and final prolapse had resolved, the animal died of natural causes. Necropsy examination exposed a large, ill-defined thickening of the distal intestinal wall, with proximal intestinal dilation. Histopathology revealed a mass composed of polygonal cells, with occasional intracytoplasmic mucin arranged in sheets, and poorly formed acini, consistent with an intestinal adenocarcinoma. A presumptive metastatic lesion was identified in the kidney (microscopically). Herpesvirus-specific consensus polymerase chain reaction (PCR) and nested PCR assays performed on the formalin-fixed, paraffin-embedded intestinal and kidney masses for ranid herpesvirus 1 were negative. Few reports of intestinal adenocarcinoma in amphibians exist in the literature. To the authors' knowledge, this represents the first report of spontaneous intestinal adenocarcinoma in a northern leopard frog.

A cold-stunned, sub-adult, female loggerhead sea turtle ( Caretta caretta ) was found stranded in December 2012 on Cape Cod, Massachusetts. The turtle was treated routinely; however, she did not gain weight as expected during rehabilitation. Eleven weeks after stranding, staff noticed stertorous upper airway sounds. Oral examination revealed a unilateral laryngeal paralysis-like condition resulting in partial airway obstruction. Magnetic resonance imaging and electromyography showed abnormalities of the abductor arytenoideae muscle. Muscle and hepatic biopsies were collected for histologic and toxicologic assessment to seek an underlying cause of the disorder. The turtle did not recover from anesthesia, and necropsy revealed a large amount of hemorrhage from the liver biopsy site. Unilateral myofiber atrophy of the abductor arytenoideae muscle was the predominant histological finding.