This article presents summative findings from a 12-month multiphase mixed-methods pilot study examining counselor and client perceptions of neuroscience-informed cognitive-behavior therapy (nCBT) following clinical application. Results from the first 6 months of the study indicated that the counselor's and client's beliefs about the credibility and effectiveness of nCBT (i.e., expectancy) remained stable from pretreatment to 6 months into treatment. The fourth phase of data collection at the 12-month interval followed an explanatory sequential process whereby the qualitative data were connected to earlier merged quantitative data to better understand initial findings from the first 6 months of the study. Results indicate that counselors' initial comprehension and familiarity with the model, counselor–client trust, counselor delivery and suggestion, and client willingness to practice outside of session were key components to the development of counselor and client belief (expectancy) in the model. Implications for nCBT theory development and application are discussed.

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