The main objective of this study was to compare the clinical and histological results of synthetic bone substitutes used in maxillary sinus floor augmentation. A systematic review and meta-analysis was performed by searching the PubMed/MEDLINE, Scopus, and Cochrane databases for studies of the success of endosseous dental implant, implant failure, peri-implant marginal bone loss, newly formed bone, and residual bone graft material. After the search, 10 randomized clinical trials were included, with 4 studies ranging from low to unclear risk of bias were used for meta-analysis, comparing biphasic calcium phosphate (BCP) and deproteinized bovine bone (DBB). A greater amount of residual graft material (mean difference [MD]: −4.80 mm; 95% CI: −9.35 to −0.26; P = .040) was found in the DBB group. No other statistically significant differences were found between BCP and DBB for the remaining outcomes. Our results suggested that BCP can be considered a suitable alternative to DBB in maxillary sinus floor augmentation due to its clinical and histological results.
Clinical and Histological Outcomes of Maxillary Sinus Floor Augmentation With Synthetic Bone Substitutes for Dental Implant Treatment: A Meta-Analysis
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Jorge Toledano-Serrabona, Aleida Romeu-i-Fontanet, Cosme Gay-Escoda, Octavi Camps-Font, Mª Ángeles Sánchez-Garcés; Clinical and Histological Outcomes of Maxillary Sinus Floor Augmentation With Synthetic Bone Substitutes for Dental Implant Treatment: A Meta-Analysis. J Oral Implantol 1 April 2022; 48 (2): 158–167. doi: https://doi.org/10.1563/aaid-joi-D-20-00202
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