The hypothesis was that probiotic therapy (PT) does not offer additional benefits to mechanical debridement (MD) for treatment of diabetic subjects with peri-implant mucositis (PM). This study compared the influence of PT as an adjunct to MD for the treatment of PM in type2 diabetic and non-diabetic patients over a 12-month follow-up period. Patients with and without type-2 diabetes were encompassed. Based upon treatment-procedure, PM patients were categorized into 2 groups: (a) Non-surgical + PT; and (b) Group-2: Non-surgical MD alone. Demographics and education statuses were recorded. Gingival (GI) and plaque (PI) indices, crestal bone loss (CBL) and probing depth (PD were measured at baseline and after 6- and 12-months. Significant differences were detected with P<0.01. The HbA1c was significantly higher in diabetic patients at all time durations than patients without type-2 diabetes (P<0.001). Baseline GI, PI, PD and CBL) were comparable in all groups. In patients with type-2-diabetes, there was no difference in PI, GI, PD and CBL at 6- and 12-months’ follow-up. In patients without type-2 diabetes, there was a significant reduction in PI (P<0.01), GI (P<0.01), and PD (P<0.01) at 6-months and 1-year follow-up than their values at baseline. In patients without type-2 diabetes, MD with or without adjunct PT reduces soft tissue inflammatory parameters in patients with PM.
Role of probiotics for the treatment of peri-implant mucositis in patients with and without type-2 diabetes mellitus
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Fawaz Alqahtani, Maha Alshaikh, Abid Mehmood, Nasser Alqhtani, Fahad Alkhtani, Adel Alenazi; Role of probiotics for the treatment of peri-implant mucositis in patients with and without type-2 diabetes mellitus. J Oral Implantol 2020; doi: https://doi.org/10.1563/aaid-joi-D-20-00302
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