Inferior alveolar nerve lateralization (IANL) is a viable treatment option for managing severely atrophic posterior mandibles with dental implants. However, this approach is frequently accompanied by postoperative neurosensory disturbance (NSD). This report described a procedure for bilateral IANL with simultaneous implant placement using 3D printing in preoperative planning and concentrated growth factor (CGF). 3D printed models enabled surgeons to gain a detailed understanding of the underlying anatomy and improve the precision of the surgical path. CGF was wrapped around the neurovascular bundle to promote the recovery of nerve function. The case revealed complete neurological recovery 2 months after surgery and stable implant osseointegration with regenerated inferior alveolar nerve wall at 6.5 years of follow-up. In addition, a literature review was performed to evaluate the outcomes of IANL and the incidence of NSD. With careful preoperative planning, appropriate procedure, and precise surgical technique, IANL can be successfully used for implant placement in the severely atrophic posterior mandibular regions.

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