This study assesses the comparative masticatory efficiency (CME) of mandibular implant-supported overdentures (ISOs) to tooth-supported overdentures (TSOs) and complete dentures (CDs). Three groups of patients in equal numbers were evaluated by assessing chewing efficiency, and the results were correlated with tracings of mandibular excursion (ME) and electromyographic (EMG) computerized analysis. CME was measured by utilizing standardized portions of 2 food staples with fixed masticatory sequencing. In a following session, utilizing the same fixed masticatory sequence, tracings of ME and EMG of the masseter and temporal muscles were recorded and analyzed. The results revealed that the ISO provided the greatest degree of efficiency, followed by the TSO and then the CD group. CME is more correlated to ME and less correlated to EMG.