Therapy based on the protective passive immunity of hyperimmune bovine colostrum (HBC) (raised against Cryptosporidium parvum in cows) was applied to 4 Savanna monitors (Varanus exanthematicus) with gastric Cryptosporidium sp. infections. All lizards were moderately emaciated, and their fecal and gastric lavage samples contained moderate numbers of Cryptosporidium sp. oocysts. The first 3 of 7 gastric HBC treatments at 1-wk interval each decreased the numbers of oocysts in the fecal and gastric samples to undetectable levels. Neither feces nor lavages of the HBC-treated lizards contained Cryptosporidium sp. oocysts after the HBC therapy, whereas such samples of a single control lizard remained positive for oocysts. Two of the HBC-treated lizards died spontaneously due to metastasized carcinoma and septicemia of unknown etiology, respectively, and 2 lizards treated and killed during the experiment were histologically negative for developmental stages of Cryptosporidium sp. The control lizard died spontaneously of septicemia of unknown etiology and contained developmental stages of Cryptosporidium sp. in the gastric region. The HBC therapy was efficacious in V. exanthematicus and is recommended for lizards with gastric cryptosporidiosis.
Skip Nav Destination
Article navigation
June 2000
RESEARCH NOTES|
June 01 2000
SUCCESSFUL HYPERIMMUNE BOVINE COLOSTRUM TREATMENT OF SAVANNA MONITORS (VARANUS EXANTHEMATICUS) INFECTED WITH CRYPTOSPORIDIUM SP
Thaddeus K. Graczyk;
Thaddeus K. Graczyk
aDepartment of Molecular Microbiology and Immunology; Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205.
bMedical Department, The Baltimore Zoo, Druid Hill Park, Baltimore, Maryland 21217.
Search for other works by this author on:
Michael R. Cranfield;
Michael R. Cranfield
aDepartment of Molecular Microbiology and Immunology; Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205.
cDivision of Comparative Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205.
Search for other works by this author on:
Eileen F. Bostwick
Eileen F. Bostwick
aDepartment of Molecular Microbiology and Immunology; Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205.
dGalaGen, Inc., Arden Hills, Minneapolis 55126
Search for other works by this author on:
J Parasitol (2000) 86 (3): 631–632.
Citation
Thaddeus K. Graczyk, Michael R. Cranfield, Eileen F. Bostwick; SUCCESSFUL HYPERIMMUNE BOVINE COLOSTRUM TREATMENT OF SAVANNA MONITORS (VARANUS EXANTHEMATICUS) INFECTED WITH CRYPTOSPORIDIUM SP. J Parasitol 1 June 2000; 86 (3): 631–632. doi: https://doi.org/10.1645/0022-3395(2000)086[0631:SHBCTO]2.0.CO;2
Download citation file:
Sign in
Don't already have an account? Register
Client Account
You could not be signed in. Please check your email address / username and password and try again.
Could not validate captcha. Please try again.
Sign in via your Institution
Sign in via your Institution
0
Views
2
Crossref
Citing articles via
MOLECULAR AND NEW MORPHOLOGICAL DATA ON NEMATODE HEDRURIS DRATINI FOUND PARASITIZING PSEUDIS MINUTA (ANURA: HYLIDAE)
Martin M. Montes, Yasmin Croci, Jorge Barneche, Dario Balcazar, German F. Reig Cardarella, Sergio R. Martorelli
CLITELLATE (ANNELIDA: CLITELLATA) PARASITES AND PREDATORS OF NORTH AMERICAN HERPETOFAUNA: CHECKLIST OF SPECIES, IDENTIFICATION KEY, AND A NEW RECORD FOR MEXICO
Manuel De Luna, Roberto García-Barrios, Diane P. Barton, Leonardo García-Vázquez
LOUSY ASSOCIATIONS: SUCKING LICE (PHTHIRAPTERA: ANOPLURA) PARASITIZING RODENTS AND LAGOMORPHS IN THE DESERT NATIONAL WILDLIFE REFUGE, NEVADA
Sara B. Weinstein, John P. Dumbacher, Lance A. Durden
A NEW SPECIES OF ACANTHOBOTHRIUM (CESTODA: ONCHOPROTEOCEPHALIDEA), PARASITE OF THE GIANT ELECTRIC RAY NARCINE ENTEMEDOR JORDAN AND STARKS, 1895 (BATOIDEA: TORPEDINIFORMES) FROM MEXICO
Erick Rodríguez-Ibarra, Berenice Adán-Torres, Fernando Ruiz-Escobar, Gerardo Torres-Carrera
SEROPREVALENCE OF TOXOPLASMA GONDII IN GOATS FROM SOUTHWESTERN MISSISSIPPI, USA
Alexander D. W. Acholonu, Jamela S. Alexander