Leishmania tropica, which is endemic in Turkey, is the causative agent of cutaneous leishmaniasis. Leishmania tropica promastigotes (2 × 107) isolated from a patient with dermal leishmaniasis and reproduced in NNN medium were inoculated subcutaneously into the footpads of 10 Balb/c mice. Cutaneous leishmaniasis developed on the footpads of 4 mice approximately 45 days later. Leishmania tropica amastigotes were observed in smear slides and then cultivated in NNN medium. Balb/c mice are a suitable laboratory model for this isolate of L. tropica and thus a source of amastigotes for studies on the immunology, chemotherapy, and pathogenicity of cutaneous leishmaniasis.
Cutaneous Leishmaniasis Infection in Balb/c Mice Using a Leishmania tropica Strain Isolated From Turkey
- Views Icon Views
- Share Icon Share
- Search Site
Nogay Girginkardeşler, İCüneyt Balcıoğlu, Kor Yereli, Ahmet Özbilgin, Yusuf Özbel; Cutaneous Leishmaniasis Infection in Balb/c Mice Using a Leishmania tropica Strain Isolated From Turkey. J Parasitol 1 October 2001; 87 (5): 1177–1178. doi: https://doi.org/10.1645/0022-3395(2001)087[1177:CLIIBC]2.0.CO;2
Download citation file: