The U6 and U5 snRNA (small nuclear ribonucleic acid) genes were identified in Taenia solium with the aim of characterizing their sequence and genomic structures. They are contained within a shared 1,009-nt tandem genomic repeat and present at approximately 3 copies per haploid genome. The U6 snRNA gene shares 92 and 95% sequence similarity with the U6 homologs from humans and Schistosoma mansoni, respectively. The U5 snRNA gene of T. solium is 70% similar to the human U5 sequence in the 5′ stem and loop 1 domains. The U6 and U5 snRNA genes are on complementary genomic strands and separated by 458 nt at their “heads” and 306 nt at their “tails.” The nucleotides upstream of the U6 gene lack a recognizable TATA box and proximal sequence elements (PSEs), and the putative gene promoter for U5 snRNA does not resemble vertebrate examples. There are short blocks of similarity between the sequences upstream of the U5 and U6 snRNA genes, and these may be sites of shared transcription factor binding at the respective RNA polymerase II and III promoters. It is possible that this unusual allied U5/U6 snRNA genomic repeat may help mediate coordinated regulation of expression of the 2 snRNAs.
Skip Nav Destination
Article navigation
April 2003
MOLECULAR-CELL BIOLOGY|
April 01 2003
THE U5/U6 snRNA GENOMIC REPEAT OF TAENIA SOLIUM Available to Purchase
Bernadette Jean-Joseph;
Bernadette Jean-Joseph
Department of Biology, California State University Northridge, 18111 Nordhoff Street, Northridge, California 91330-8303. [email protected]
Search for other works by this author on:
Ana Flisser;
Ana Flisser
Department of Biology, California State University Northridge, 18111 Nordhoff Street, Northridge, California 91330-8303. [email protected]
* Departamento de Microbiologia y Parasitologia, Facultad de Medicina, Edificio A, 2do Piso, Universidad Nacional Autónoma de México, Circuito Interior, Ciudad Universitaria, CP 04510 México, Mexico
Search for other works by this author on:
Ariadna Martinez;
Ariadna Martinez
Department of Biology, California State University Northridge, 18111 Nordhoff Street, Northridge, California 91330-8303. [email protected]
† Present address: Department of Psychiatry, University of California, Los Angeles, California 90024
Search for other works by this author on:
Stan Metzenberg
Stan Metzenberg
Department of Biology, California State University Northridge, 18111 Nordhoff Street, Northridge, California 91330-8303. [email protected]
‡ To whom correspondence should be addressed
Search for other works by this author on:
J Parasitol (2003) 89 (2): 329–335.
Citation
Bernadette Jean-Joseph, Ana Flisser, Ariadna Martinez, Stan Metzenberg; THE U5/U6 snRNA GENOMIC REPEAT OF TAENIA SOLIUM. J Parasitol 1 April 2003; 89 (2): 329–335. doi: https://doi.org/10.1645/0022-3395(2003)089[0329:TUSGRO]2.0.CO;2
Download citation file:
Sign in
Don't already have an account? Register
Client Account
You could not be signed in. Please check your email address / username and password and try again.
Could not validate captcha. Please try again.
Sign in via your Institution
Sign in via your InstitutionCiting articles via
HAPLOTYPE DIVERSITY IN ENDOSYMBIOTIC BACTERIA FOLLOWING A HOST SWITCH BY PARASITIC LICE
Bret M. Boyd, Niyomi House, Ariel C. Toloza, David L. Reed
DESCRIPTION, REDESCRIPTION, AND LIFE CYCLES OF CLOACITREMA KURISI N. SP. AND CLOACITREMA MICHIGANENSIS (TREMATODA: DIGENEA: PHILOPHTHALMIDAE) FROM THE CALIFORNIA HORN SNAIL, CERITHIDEOPSIS CALIFORNICA (GASTROPODA: POTAMIDIDAE)
Alexandria P. Nelson, Daniel C. G. Metz, Ryan F. Hechinger
A NEW SPECIES OF HALIPEGUS (TREMATODA: DEROGENIDAE: HALIPEGINAE) IN LITHOBATES SPECTABILIS (ANURA: RANIDAE) FROM RESERVA DE LA BIOSFERA BARRANCA DE METZTITLAN, HIDALGO, MEXICO
Edgar S. Ramírez-Cruz, Griselda Pulido-Flores, Scott Monks, Elizabeth A. Martínez-Salazar
A SYSTEMATIC REVISION OF KROYERIA (COPEPODA: SIPHONOSTOMATOIDA): FIVE NEW SPECIES, 11 REDESCRIPTIONS, AND A MORPHOLOGICAL PHYLOGENETIC ANALYSIS OF THE GENUS
Gregory B. Deets, Geoffrey A. Boxshall, James P. Bernot
MOLECULAR SURVEY OF HAEMOSPORIDIAN PARASITES IN HAWKS, FALCONS, AND OWLS (ACCIPITRIFORMES, FALCONIFORMES, STRIGIFORMES) FROM MINNESOTA AND NORTH DAKOTA, WITH REMARKS ON THE PHYLOGENETIC RELATIONSHIPS OF HAEMOSPORIDIANS IN NORTH AMERICAN RAPTORS
Jeffrey A. Bell, Timothy G. Driscoll, Tyler J. Achatz, Jakson R. Martens, Jefferson A. Vaughan