The spore of Myxosoma cerebralis is redescribed and compared with that of a close relative, M. cartilaginis. M. cerebralis is smaller, with greater variability in size and shape. It possesses a mucous envelope whereas M. cartilaginis does not. The surface architecture of M. cerebralis, as seen with the scanning electron microscope, differs in possessing a conspicuous circumsutural groove, prominent polar filament pores, and a mucous envelope.

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