Magnetic resonance (MR) imaging has been suggested to be helpful in delineating the lesions during the acute phase of angiostrongyliasis caused by Angiostrongylus cantonensis. In this study, antibody titers in serum samples of 3 rabbits were determined by enzyme-linked immunosorbent assay, and brain MR images were obtained from 6 rabbits. The antibody titer elevated rapidly in the first 4 wk postinfection (PI) before reaching a plateau. However, suspicious changes in brain MR images near the left lateral ventricle and hippocampus were found only in 1 rabbit on day 28 PI. These findings indicate that immunologic responses in the central nervous system at the early stage of angiostrongyliasis are not sufficient to be observed by image studies.
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October 2004
RESEARCH NOTES|
October 01 2004
Alteration of Antibodies Against the Fifth-Stage Larvae and Changes in Brain Magnetic Resonance Images in Experimentally Infected Rabbits with Angiostrongylus cantonensis
Lian-Chen Wang;
Lian-Chen Wang
aDepartment of Parasitology, School of Medicine, Chang-Gung University, Kueisan, Taoyuan, Taiwan (333)
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Yung-Liang Wan
Yung-Liang Wan
bDepartment of Diagnostic Radiology, Chang-Gung Memorial Hospital at Linkou, School of Medicine and Medical Technology, Chang Gung University, Kueisan, Taoyuan, Taiwan (333)
cTo whom correspondence should be addressed. [email protected]
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J Parasitol (2004) 90 (5): 1193–1196.
Citation
Lian-Chen Wang, Yung-Liang Wan; Alteration of Antibodies Against the Fifth-Stage Larvae and Changes in Brain Magnetic Resonance Images in Experimentally Infected Rabbits with Angiostrongylus cantonensis. J Parasitol 1 October 2004; 90 (5): 1193–1196. doi: https://doi.org/10.1645/GE-319R
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