We investigated Toxoplasmosis gondii antibody seroprevalence in free-ranging caracals (Caracal caracal) in Cape Town, South Africa, from 2014 to 2017. Seropositivity was 83% (24/29), which is substantially higher than that detected in sympatric feral domestic cat (Felis catus) populations. The impact of this pathogen on local human and wildlife communities may be of concern.

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