The radiation response of SCCVII tumor cells in C3H/He mice under various irradiation conditions was studied using an in vivo-in vitro assay. When tumor-bearing mice were irradiated without anesthesia or physical restraint, the tumor had a hypoxic fraction of 5.4%. Both anesthesia and immobilization of the tumor-bearing leg with adhesive tape produced significant increases in the hypoxic fraction (23 and 28%, respectively). Restraining the mouse in a jig without immobilizing the tumor-bearing leg also increased the hypoxic fraction (13%).
The Radiation Response of SCCVII Tumor Cells in C3H/He Mice Varies with the Irradiation Conditions
- Views Icon Views
- Share Icon Share
- Search Site
Yuta Shibamoto, Keisuke Sasai, Mitsuyuki Abe; The Radiation Response of SCCVII Tumor Cells in C3H/He Mice Varies with the Irradiation Conditions. Radiat Res 1 February 1987; 109 (2): 352–354. doi: https://doi.org/10.2307/3576961
Download citation file: