The sonolysis of aqueous solutions of various dihydropyrimidines and substituted pyrimidines was investigated by ESR and spin trapping with the nonvolatile, water soluble spin trap, 3,5-dibromonitrosobenzene sulfonate (DBNBS) and its deuterated analog to examine the possibility of detecting new radicals specifically generated in the high temperature zones produced by collapsing cavitation bubbles. Similar ESR spectra were obtained from sonolysis of argon-saturated aqueous solutions, from uv photolysis of aqueous solutions containing H2 O2, and from γ radiolysis of nitrous oxide saturated solutions, although sonolysis of aqueous solutions leads to the formation of pyrimidine radicals by H atom as well as OH radical addition to the 5,6 double bond of pyrimidines. No evidence for specific new radicals formed in the high temperature regions induced by cavitation could be found. For the reactions of dihydropyrimidines with hydroxyl radicals additional spin adducts could be detected and identified with the spin trap DBNBS compared to 2-methyl-2-nitrosopropane which was used in previous studies; however, for alkylpyrimidines fewer spin adducts were observed. The use of the deuterated analog of DBNBS is helpful for unambiguous radical structure assignment.
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October 1988
Research Article|
October 01 1988
Sonolysis, Radiolysis, and Hydrogen Peroxide Photolysis of Pyrimidine Derivatives in Aqueous Solutions: A Spin-Trapping Study
Radiat Res (1988) 116 (1): 56–73.
Citation
Takashi Kondo, C. Murali Krishna, Peter Riesz; Sonolysis, Radiolysis, and Hydrogen Peroxide Photolysis of Pyrimidine Derivatives in Aqueous Solutions: A Spin-Trapping Study. Radiat Res 1 October 1988; 116 (1): 56–73. doi: https://doi.org/10.2307/3577478
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