The rate coefficients in the model of cell kinetics and mortality introduced by Jones et al. (Radiat. Res. 128, 258-266 (1991)) are estimated using mortality data from several mouse experiments. The evaluated model fits data from a large variety of prompt, protracted, and fractionated irradiations with 250-k Vp X rays with good fidelity. Although the maximum-likelihood estimates are not unique, all estimates lead to greater cell survival than that observed in in vitro experiments on nonterminally differentiated reproducing cells from the marrow.
Estimation of Coefficients in a Model of Radiation-Induced Myelopoiesis from Mortality Data for Mice Following X-Ray Exposure
- Views Icon Views
- Share Icon Share
- Search Site
Max D. Morris, Troyce D. Jones, Robert W. Young; Estimation of Coefficients in a Model of Radiation-Induced Myelopoiesis from Mortality Data for Mice Following X-Ray Exposure. Radiat Res 1 December 1991; 128 (3): 267–275. doi: https://doi.org/10.2307/3578049
Download citation file: