A nested case control study of persons who developed skin cancer after scalp irradiation in childhood revealed two risk factors for the appearance of radiation-induced skin cancer: (a) an apparently higher radiation dose delivered inadvertently, manifested by a higher prevalence of alopecia and radiation dermatitis (RR = 3.4; CI 1.3-8.8); (b) a more frequent exposure to the sun, manifested by summer sunbathing (RR = 2.6; CI 1.1-6.1). These findings may have certain implications with regard to the understanding of radiation-induced cancer, after low-dose radiation exposure, in general.
Factors Affecting the Development of Skin Cancer after Scalp Irradiation
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Baruch Modan, Esther Alfandary, Dorit Shapiro, Ayala Lusky, Angela Chetrit, Miriam Shewach-Millet, Moshe Movshovitz; Factors Affecting the Development of Skin Cancer after Scalp Irradiation. Radiat Res 1 July 1993; 135 (1): 125–128. doi: https://doi.org/10.2307/3578405
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