Johannes et al. (1) recently presented interesting new data on the LET dependence of intrachromosomal aberration yields, which may be compared with earlier theoretical calculations and experimental results. Specifically, Johannes et al. reported that their measured ratios of intrachromosomal to interchromosomal aberrations were independent of LET, in contrast to some in vitro measurements (2), in vivo results (3), and theoretical expectations (4 ,5). We suggest there may be two reasons for this discrepancy:

Thus comparisons between the data for low-LET and high-LET radiation from Johannes et al. (1) are hard to make because of the different techniques used and because of the mixed field used for the exposures at high LET. It may be, therefore, that the results of Johannes et al. are not in disagreement with earlier experimental results, in which...

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