The title of my presentation prompted several to remind me of the futility of chasing free radicals given their fleeting lifetimes. Nonetheless, I have been a chaser of free radicals much of my career. Admittedly, my first 10 years of radiation research was spent studying the “aftermath” of radiation-induced free radical damage under the guidance of Joel Bedford. Joel was Eric Hall's first Ph.D. student and I was Joel's first student and all three of us were dedicated to unraveling the biology underlying the dose-rate effect, particularly for continuous low-dose-rate radiation (Fig. 1A). Joel provided me fertile ground for research and taught me the basics of experimental design and the importance of controls and the subtleties of responding to reviewers and sometimes critics. Continuous low-dose-rate radiation was found to block cells in G2 with subsequent accumulation in mitosis resulting over a specific...
Skip Nav Destination
Research Article| July 01 2011
- Views Icon Views
- Share Icon Share
- Search Site
James B. Mitchell; Chasing Free Radicals in Cells and Tissues. Radiat Res 1 July 2011; 176 (1): 1–7. doi: https://doi.org/10.1667/RR2626.1
Download citation file:
Citing articles via
Commonalities Between COVID-19 and Radiation Injury
Carmen I. Rios, David R. Cassatt, Brynn A. Hollingsworth, Merriline M. Satyamitra, Yeabsera S. Tadesse, Lanyn P. Taliaferro, Thomas A. Winters, Andrea L. DiCarlo
Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks?
Pataje G. Prasanna, Gayle E. Woloschak, Andrea L. DiCarlo, Jeffrey C. Buchsbaum, Dörthe Schaue, Arnab Chakravarti, Francis A. Cucinotta, Silvia C. Formenti, Chandan Guha, Dale J. Hu, Mohammad K. Khan, David G. Kirsch, Sunil Krishnan, Wolfgang W. Leitner, Brian Marples, William McBride, Minesh P. Mehta, Shahin Rafii, Elad Sharon, Julie M. Sullivan, Ralph R. Weichselbaum, Mansoor M. Ahmed, Bhadrasain Vikram, C. Norman Coleman, Kathryn D. Held
Germicidal Efficacy and Mammalian Skin Safety of 222-nm UV Light
Manuela Buonanno, Brian Ponnaiya, David Welch, Milda Stanislauskas, Gerhard Randers-Pehrson, Lubomir Smilenov, Franklin D. Lowy, David M. Owens, David J. Brenner