In this study we analyzed the ESR signal of alanine dosimeters with gadolinium exposed to 6 MV linear accelerator photons. We observed that the addition of gadolinium brings about an improvement in the sensitivity to photons because of its high atomic number. The experimental data indicated that the addition of gadolinium increases the sensitivity of the alanine to 6 MV photons. This enhancement was better observed at high gadolinium concentrations for which the tissue equivalence is heavily reduced. However, information about the irradiation setup and of the radiation beam features allows one to correct for this difference. Monte Carlo simulations were carried out to obtain information on the expected effect of the addition of gadolinium on the dose absorbed by the alanine molecules inside the pellets. These results are compared with the experimental values, and the agreement is discussed.
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1 December 2011
Research Article|
August 08 2011
Sensitivity of Alanine Dosimeters with Gadolinium Exposed to 6 MV Photons at Clinical Doses
M. Marrale
;
M. Marrale
1
aDipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo, Italy
cUnità CNISM, Palermo and Gruppo V, Sezione INFN, Catania
1Address for correspondence: Dipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo, Italy; e-mail: maurizio.marrale@unipa.it.
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A Longo
;
A Longo
aDipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo, Italy
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M. Spanò
;
M. Spanò
aDipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo, Italy
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A. Bartolotta
;
A. Bartolotta
bDipartimento STEMBIO, Settore Farmacochimico, Tossicologico e Biologico Università Di Palermo, via M. Cipolla 74d 90123 Palermo, Italy
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M. C. D'Oca
;
M. C. D'Oca
bDipartimento STEMBIO, Settore Farmacochimico, Tossicologico e Biologico Università Di Palermo, via M. Cipolla 74d 90123 Palermo, Italy
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M. Brai
M. Brai
aDipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo, Italy
cUnità CNISM, Palermo and Gruppo V, Sezione INFN, Catania
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Radiat Res (2011) 176 (6): 821–826.
Article history
Received:
April 19 2010
Accepted:
July 08 2011
Citation
M. Marrale, A Longo, M. Spanò, A. Bartolotta, M. C. D'Oca, M. Brai; Sensitivity of Alanine Dosimeters with Gadolinium Exposed to 6 MV Photons at Clinical Doses. Radiat Res 1 December 2011; 176 (6): 821–826. doi: https://doi.org/10.1667/RR2256.1
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